#lv-ic50-calculator {
  background: #ffffff;
}

#lv-ic50-calculator .lv-calc-header p {
  max-width: 900px;
}

#lv-ic50-calculator .lv-dose-hero {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 10px;
  margin: 14px auto 18px;
}

#lv-ic50-calculator .lv-dose-hero-line {
  display: block;
  width: 52px;
  height: 2px;
  border-radius: 999px;
  background: var(--lv-blue);
  opacity: 0.25;
}

#lv-ic50-calculator .lv-dose-hero-icon {
  width: 92px;
  height: 58px;
  overflow: visible;
}

#lv-ic50-calculator .lv-dose-axis {
  fill: none;
  stroke: #b8c7d9;
  stroke-width: 1.4;
}

#lv-ic50-calculator .lv-dose-curve {
  fill: none;
  stroke: var(--lv-blue);
  stroke-linecap: round;
  stroke-width: 3;
}

#lv-ic50-calculator .lv-dose-controls {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 18px;
  margin-bottom: 18px;
}

#lv-ic50-calculator .lv-dose-input-grid {
  grid-template-columns: minmax(0, 1.4fr) minmax(180px, 0.6fr);
}

#lv-ic50-calculator .lv-segmented-control {
  display: grid;
  grid-template-columns: repeat(var(--lv-segment-count), minmax(0, 1fr));
  width: 100%;
  padding: 3px;
  border: 1px solid var(--lv-border);
  border-radius: 13px;
  background: #eef2f7;
  position: relative;
  overflow: hidden;
  --lv-segment-count: 2;
  --lv-active-index: 0;
}

#lv-ic50-calculator .lv-segmented-indicator {
  position: absolute;
  top: 3px;
  bottom: 3px;
  left: 3px;
  width: calc((100% - 6px) / var(--lv-segment-count));
  border-radius: 10px;
  background: #ffffff;
  box-shadow: 0 4px 12px rgba(17, 24, 39, 0.08);
  transform: translateX(calc(var(--lv-active-index) * 100%));
  transition: transform 180ms ease;
  z-index: 0;
  pointer-events: none;
}

#lv-ic50-calculator .lv-segmented-option {
  display: flex;
  align-items: center;
  justify-content: center;
  min-height: 38px;
  padding: 8px 12px;
  border: 0;
  border-radius: 10px;
  background: transparent;
  color: var(--lv-muted);
  font-family: var(--lv-font);
  font-size: 13px;
  font-weight: 800;
  text-align: center;
  cursor: pointer;
  position: relative;
  z-index: 1;
}

#lv-ic50-calculator .lv-segmented-option:nth-of-type(1) {
  grid-column: 1;
  grid-row: 1;
}

#lv-ic50-calculator .lv-segmented-option:nth-of-type(2) {
  grid-column: 2;
  grid-row: 1;
}

#lv-ic50-calculator .lv-segmented-option.lv-active {
  color: var(--lv-blue);
}

#lv-ic50-calculator .lv-panel-heading-row {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
  gap: 16px;
}

#lv-ic50-calculator .lv-example-btn {
  flex: 0 0 auto;
  white-space: nowrap;
}

#lv-ic50-calculator .lv-dose-data-input {
  min-height: 230px;
  font-family: Consolas, "Courier New", monospace;
  resize: vertical;
}

#lv-ic50-calculator .lv-primary-result-grid {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  gap: 12px;
  margin-bottom: 18px;
}

#lv-ic50-calculator .lv-primary-metric {
  padding: 16px;
  border: 1px solid var(--lv-border);
  border-radius: 14px;
  background: #ffffff;
}

#lv-ic50-calculator .lv-primary-metric-label {
  color: var(--lv-muted);
  font-size: 13px;
  font-weight: 700;
}

#lv-ic50-calculator .lv-primary-metric-value {
  margin-top: 6px;
  color: var(--lv-navy);
  font-size: 20px;
  font-weight: 800;
  line-height: 1.25;
}

#lv-ic50-calculator .lv-results-shell-grid {
  display: grid;
  grid-template-columns: minmax(0, 0.86fr) minmax(0, 1.14fr);
  gap: 16px;
}

#lv-ic50-calculator .lv-results-shell-grid .lv-export-card {
  margin-top: 0;
}

#lv-ic50-calculator .lv-results-wide {
  grid-column: 1 / -1;
}

#lv-ic50-calculator .lv-quality-grid {
  display: grid;
  gap: 10px;
}

#lv-ic50-calculator .lv-quality-row {
  display: flex;
  justify-content: space-between;
  gap: 12px;
  padding: 9px 0;
  border-bottom: 1px solid #e5e7eb;
}

#lv-ic50-calculator .lv-quality-row:last-child {
  border-bottom: 0;
}

#lv-ic50-calculator .lv-quality-label {
  color: var(--lv-muted);
}

#lv-ic50-calculator .lv-quality-value {
  color: var(--lv-navy);
  font-weight: 800;
  text-align: right;
}

#lv-ic50-calculator .lv-results-table-wrap {
  width: 100%;
  overflow-x: auto;
}

#lv-ic50-calculator .lv-results-table {
  width: 100%;
  min-width: 720px;
  border-collapse: collapse;
}

#lv-ic50-calculator .lv-results-table th,
#lv-ic50-calculator .lv-results-table td {
  padding: 10px 8px;
  border-bottom: 1px solid #e5e7eb;
  text-align: left;
  vertical-align: top;
}

#lv-ic50-calculator .lv-results-table th {
  background: var(--lv-bg);
  color: var(--lv-navy);
  font-size: 12px;
  white-space: nowrap;
}

#lv-ic50-calculator .lv-graph-placeholder {
  display: flex;
  align-items: center;
  justify-content: center;
  min-height: 280px;
  border: 1px dashed var(--lv-border);
  border-radius: 14px;
  background: linear-gradient(180deg, rgba(45, 108, 223, 0.07), rgba(255, 255, 255, 0.9));
  color: var(--lv-muted);
  font-weight: 700;
}

#lv-ic50-calculator .lv-dose-chart {
  width: 100%;
  min-height: 360px;
}

#lv-ic50-calculator .lv-dose-chart text {
  font-family: var(--lv-font);
  fill: var(--lv-muted);
}

#lv-ic50-calculator .lv-chart-axis {
  stroke: #d7e0ea;
  stroke-width: 1;
}

#lv-ic50-calculator .lv-chart-grid {
  stroke: #edf2f7;
  stroke-width: 1;
}

#lv-ic50-calculator .lv-chart-curve {
  fill: none;
  stroke: var(--lv-blue);
  stroke-linecap: round;
  stroke-linejoin: round;
  stroke-width: 3;
}

#lv-ic50-calculator .lv-chart-point {
  fill: #ffffff;
  stroke: var(--lv-blue);
  stroke-width: 2;
}

#lv-ic50-calculator .lv-chart-error,
#lv-ic50-calculator .lv-chart-marker {
  stroke: var(--lv-brand-dark);
  stroke-linecap: round;
  stroke-width: 1.6;
}

#lv-ic50-calculator .lv-chart-marker {
  stroke-dasharray: 5 4;
  opacity: 0.78;
}

#lv-ic50-calculator .lv-chart-midline {
  stroke: #9fb4ca;
  stroke-dasharray: 4 4;
  stroke-width: 1.2;
}

#lv-ic50-calculator .lv-flag-text {
  color: var(--lv-yellow-text);
  font-weight: 800;
}

@media (max-width: 850px) {
  #lv-ic50-calculator .lv-dose-controls,
  #lv-ic50-calculator .lv-dose-input-grid,
  #lv-ic50-calculator .lv-results-shell-grid,
  #lv-ic50-calculator .lv-primary-result-grid {
    grid-template-columns: 1fr;
  }

  #lv-ic50-calculator .lv-panel-heading-row {
    display: grid;
  }

  #lv-ic50-calculator .lv-example-btn {
    width: 100%;
  }
}